Ten-year estimated risk of bone fracture in women with differentiated thyroid cancer under TSH-suppressive levo-thyroxine therapy
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چکیده
منابع مشابه
TSH-suppressive treatment in differentiated thyroid cancer. A dogma under review.
TSH-suppressive therapy (ST) is part of the treatment protocol for differentiated thyroid carcinoma (DTC). There is however little evidence of its clinical effectiveness. On the other side, ST is not free from side effects related to the subclinical hyperthyroidism status induced in patients for a long time period. Because of this, widespread use of ST in all patients has recently been question...
متن کاملHip bone mineral density, bone turnover and risk of fracture in patients on long-term suppressive L-thyroxine therapy for differentiated thyroid carcinoma.
OBJECTIVE Untreated hyperthyroidism and treatment with high doses of thyroid hormone are associated with osteoporosis. However, their effect on bone turnover, their contribution to bone mineral density (BMD) in the context of other clinical risk factors for osteoporosis and the prevalence of vertebral fractures is not well documented. DESIGN Cross-sectional study. METHODS We studied 59 pati...
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Background and Objective: Patients with hypothyroidism require thyroid hormone replacement. Many studies have shown that bone density reduction is caused by suppressive doses of levothyroxine, but there are contradictory results regarding the effect of levothyroxine replacement dose (non suppressive). The purpose of this study was to investigate the effect of replacement doses of levothyroxine ...
متن کاملRadioiodine treatment of metastatic differentiated thyroid cancer in patients on L-thyroxine, using recombinant human TSH.
OBJECTIVE This study tested the hypothesis that administration of human recombinant thyroid-stimulating hormone (rhTSH: Thyrogen, thyrotropin alpha) could promote iodine-131 ((131)I) uptake in the therapy for metastatic or locally invasive differentiated thyroid cancer (DTC), obviating L-thyroxine suppressive therapy (L-T4) withdrawal and hypothyroidism in patients with advanced disease. METH...
متن کاملThyroid hormone replacement one day before 131I therapy in patients with well-differentiated thyroid cancer
Objective: The current study aimed to determine the efficacy of radioiodine-131 (131I) ablation therapy with thyroid hormone replacement one day before 131I administration in patients with well-differentiated thyroid cancer (DTC). Methods: This retrospective study included 29 patients who underwent 131I therapies twice for DTC during 6-12 months. Since all the patients obviously had residual l...
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ژورنال
عنوان ژورنال: Endokrynologia Polska
سال: 2015
ISSN: 2299-8306,0423-104X
DOI: 10.5603/ep.a2016.0046